摘要:
目的 探讨长期低浓度接触混合有机溶剂对制鞋作业工人肝脏的影响。 方法 对生产车间使用甲苯、苯、二氯乙烷、正己烷等混合有机溶剂的某鞋业工厂347名工人(接触组)和工厂无毒物接触史后勤人员321人(对照组)进行肝脏B超检查,比较两组检查结果。 结果 生产车间使用的有机溶剂的时间加权平均浓度均未超过职业接触限值。接触组弥漫性肝回声音改变、肝大的检出率均高于对照组,上述指标在两组间比较,差异均有统计学意义(χ2=27.8、12.5,P<0.05)。将两组各分成6个工龄段,弥漫性肝回声改变的检出率在工龄大于等于2年(4个工龄段)的两组员工间比较,差异均有统计学意义(χ2=8.9、10.2、10.2、10.5,P<0.05),两组的异常检出率均随着工龄的增加而升高。 结论 较长时间接触混合有机溶剂对作业工人肝脏可能存在慢性损害,应注意预防。
+ English
Abstract:
Objective To observe the adverse effect of long-term exposure to mixed organic solvents on liver among workers in a shoe factory. Methods The occupational health examination data, particularly liver B-ultrasonography data of 347 workers exposed to mixed organic solvents including toluene, benzene, dichloroethane and n-hexane, and the occupational health examination data of 321 workers without exposure to occupational hazards in this shoe factory were analyzed. Results The working environment monitoring showed that the TWA concentration of these solvents at workplaces was lower than the national exposure limits. However, the liver B-ultrasonography showed that the detective rates of hepatomegaly and change of hepatic diffuse echo among exposed workers were significantly higher than those among workers without exposure to occupational hazards(χ2=27.8、12.5,P<0.05),and the change of hepatic diffuse echo happened more often among the workers with employment history of more than 2 years. Conclusion Long term exposure to mixed organic solvents may cause chronic liver damage among occupationally exposed workers, which should be paid attention to.
百度学术
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