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Responsible InstitutionShanghai Municipal Commission of Health

Sponsor Shanghai Institute of Occupational Disease for Chemical Industry Shanghai Institute of Occupational Safety and Health


ISSN 1007-1326 CN 31-1719/R

Articles in press have been peer-reviewed and accepted, which are not yet assigned to volumes /issues, but are citable by Digital Object Identifier (DOI).
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2023, 41(1): 0-0.  
[Abstract](18) [PDF 9178KB](4)
Special article: construction of health emergency response capacity in China
Poisoning control to protect public health
ZHANG Meibian
2023, 41(1): 1-1.  
[Abstract](0) [FullText HTML](0) [PDF 0KB](0)
Current situation of poison hazard and response strategies
SUN Chengye
2023, 41(1): 2-3.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.001
[Abstract](11) [FullText HTML](1) [PDF 294KB](7)
Construction and capacity building of health emergency response system for acute poisoning accidents in China
ZHOU Jing, ZHANG Meibian
2023, 41(1): 4-9.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.002
[Abstract](9) [FullText HTML](0) [PDF 921KB](9)
Legal guarantee and standard and normative system construction related to health emergency response to acute poisoning accidents in China
ZHANG Hongshun
2023, 41(1): 10-14.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.003
[Abstract](9) [FullText HTML](0) [PDF 696KB](6)
Investigation on current situation of emergency responses to acute poisoning accidents in various-level centers for disease control and prevention in China
ZHOU Jing, YUAN Yuan, LANG Nan, SUN Chengye
2023, 41(1): 15-19.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.004
[Abstract](10) [FullText HTML](0) [PDF 622KB](6)
Upgrade and practice of health emergency information platform for acute poisoning accidents
LANG Nan, ZHANG Yutao, JIANG Shaofeng, YUAN Yuan, SUN Chengye, ZHANG Hongshun, ZHOU Jing
2023, 41(1): 20-23.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.005
[Abstract](11) [FullText HTML](1) [PDF 785KB](5)
  Objective  The health emergency information platform for acute poisoning accidents was upgraded through system reconstruction and new technology application to rationalize functional structure and solve the problems of data redundancy and unfriendly interaction.  Methods  The rules of health emergency disposal and health emergency preparedness were systematically analyzed, and the reporting process was optimized. To adapt to the new requirements of system network security, a micro-services architecture website was applied to construct a new platform.  Results  On the upgraded platform, the modules including home page work center, poisoning public opinion, and poisoning consultation were added; the modules of reporting and query were integrated; the statistical analysis function was redesigned; and some of the form content was modified so that the effective integration of various functions, such as reporting, querying, submission, auditing, and reviewing, can be achieved.  Conclusions  The improved poisoning information platform system can more safely and reliably serve poisoning health emergency management, assist in comprehensively and dynamically grasping the work status of all poisoning emergency institutions at all levels, and provide support for poisoning capacity evaluation, scientific planning, and construction.
Construction and application of poison information database and toxic animal and plant specimen digit repository platform system
YIN Yu, JIANG Shaofeng, ZHANG Hongshun, SUN Chengye
2023, 41(1): 24-27.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.006
[Abstract](10) [FullText HTML](0) [PDF 551KB](5)
  Objective  A poison database with comprehensive and accurate poison information was constructed in order to provide professional support for emergency response personnel and medical staff at all levels to deal with all kinds of poisoning incidents in a correct, timely, and standardized manner.  Methods  A database framework including the physical and chemical properties, toxicity, on-site treatment, on-site rescue, clinical treatment, and other information of poisons was established, based on both standardized classifications of poisons and structured information. The database information content was constructed on the basis of reliable information sources and through the steps of collection, sorting, review, warehousing, and release. The data query function was achieved by both precise querying and fuzzy querying.  Results  This database consists of 30 information unit modules with more than 500 data sets. It contains textual information on 16 720 toxicants, 7 053 toxicant picture information records, and 20 633 poison control-related records.  Conclusions  This database is the largest Chinese poison database, which can provide the most powerful information and data support for emergency disposal of sudden poisoning events and treatment of poisoned patients in China.
Investigation on reserve of common used antidotes in the appointed medical institutions for poisoning treatment in China and thinking on improvement of reserve mechanism
ZHOU Jing, LANG Nan, YUAN Yuan, SUN Chengye
2023, 41(1): 28-32.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.007
[Abstract](11) [FullText HTML](0) [PDF 638KB](5)
  Objective  To understand the reserve, application, and transfer of common used antidotes in the appointed medical institutions for poisoning treatment in China, and to provide reference for the research and development, production, and reserve of antidotes.  Methods  Totally 150 provincial poisoning treatment bases and appointed medical institutions for poisoning treatment at the provincial, municipal and county levels were cross-sectionally surveyed. The antidotes reserve condition was evaluated, based on the results of 2018 national survey on the basic situation of poisoning health emergency.  Results  Totally 136 medical institutions reported their reserves of antidotes, and 124 filled in the reserve list. 79.41% (108/136) medical institutions reserved antidotes, and 92.65% (126/136) institutions regularly renewed these antidotes. The proportion of medical institutions in reserve of 14 drugs listed in catalogue of 24 common used antidotes was less than 10%. 43.38% (59/136) of the medical institutions thought the reserves of antidotes did not meet the requirement. 44.12% (60/136) medical institutions reported that being out-of-stock was the main problem affecting their reserve of antidotes. 63.24% (86/136) institutions thought that there were fewer types of antidotes available.  Conclusions  The medical institutions appointed for poisoning treatment had difficulties in reserving antidotes. The types of antidotes cannot meet the requirements of daily treatment and health emergencies. The mechanisms of production, supply, and reserve of antidotes urgently need to be optimized. It is necessary to increase support for research and development of antidotes, establish a green channel for antidotes approval, and improve the ways to obtain information on the reserves of antidotes.
Characteristics of counseling cases related to pesticide poisoning from 2011 to 2020 and discussion on control strategies
JIANG Shaofeng, YIN Yu, ZHANG Yutao, HE Qian, CHENG Bowen, MA Peibin, ZHOU Jing, SUN Chengye, ZHANG Hongshun
2023, 41(1): 33-36.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.008
[Abstract](8) [FullText HTML](0) [PDF 706KB](5)
  Objective  To understand the characteristics of counseling cases related to pesticide poisoning, and the pesticide spectrum that caused poisoning, to explore the impact of pesticide management regulations on pesticide poisoning control, and to provide a reference for the prevention and control strategy of pesticide poisoning.  Methods  The data of national consultation cases of pesticide poisoning from 2011 to 2020 were collected, the counseling time, region, type of pesticide poisoning, gender and age distribution were analyzed, and the effects of policies on pesticide poisoning were discussed.  Results  There were a total of 16 683 counseling cases of pesticide poisoning from 2011 to 2020, with a gender ratio of 1.28∶1, and the most cases were concentrated in May. The top five provinces for counseling cases were Henan (2 428, 14.55%), Hebei (1 635, 9.80%), Shandong (1 435, 8.60%), Anhui (1 304, 7.82%) and Jiangsu (926, 5.55%). The number of pesticide poisoning counseling cases decreased year over year. 9 469 poisoning cases were caused by insecticides (accounting for 56.76%), 4 371 cases were caused by herbicides (accounting for 26.20%), and 1 609 poisoning cases were caused by fungicides with low toxicity (accounting for 9.64%). Totally, 15 786 counseling cases were due to self- medication, misuse, accidents, and occupational exposure. The highest proportion of self-medication was in 7 763 cases, accounting for 46.53%, followed by misuse (4 438 cases, accounting for 26.60%) and occupational exposure (2 850 cases accounting for 17.08%). There was a statistical difference of poisoning causes between men and women (P < 0.01), men were more affected by occupational exposure and women were more affected by self-medication. Misuse was the most common cause for the infants aged 6 years and below, with a sex ratio of 2.56∶1, while self-medication and occupational exposure were the main causes for adults over 18 years old.  Conclusions  The characteristics of counseling cases related to pesticide poisoning were obvious. The number of counseling cases has been significantly reduced since the use of (extremely) toxic pesticides has been banned or restricted. Policy intervention has a significant effect on the control of pesticide poisoning, and targeted prevention and control measures should be continuously taken in different populations and regions to reduce the occurrence of pesticide poisoning.
Characteristics of acute occupational poisoning cases reported in China from 2004 to 2021
YUAN Yuan, HE Qian, WANG Dan, ZHOU Jing, LANG Lan, YIN Yu, ZHANG Meibian, SUN Chengye
2023, 41(1): 37-42.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.009
[Abstract](10) [FullText HTML](0) [PDF 727KB](5)
  Objective  In order to provide the scientific basis for the prevention, control and management of acute occupational poisoning incidents, the characteristics and the occurrence pattern of acute occupational poisoning incidents in China from 2004 to 2021 were analyzed.  Methods  The data of acute occupational poisoning incidents reported in the management information system of public health emergency in China CDC were collected, the information such as date of occurrence, region of occurrence, number of poisoning, number of deaths, occupational hazards, industry and enterprise size was abstracted and analyzed.  Results  From 2004 to 2021, a total of 528 acute occupational poisoning incidents were reported in 28 provinces (municipalities autonomous regions) and the Xinjiang Production and Construction Corps, resulting in 5 426 poisoning cases and 600 deaths, with a fatality rate of 11.1%. 301 incidents (accounting for 57.0%) were reported by Shanghai, Anhui, Shandong, Yunnan and Sichuan. The highest number of incidents and deaths of acute occupational poisoning were reported in August, with 64 cases (accounting for 12.1%) and 89 deaths (accounting for 14.8%). The number of acute occupational poisoning incidents and deaths caused by asphyxiating and irritant gases accounted for 69.9% and 82.0%, respectively. Carbon monoxide and hydrogen sulfide poisoning accounted for 82.9% of the asphyxiation gas poisoning incidents. Chlorine, ammonia, phosgene, nitrogen oxide and dimethyl sulfate poisoning accounted for 57.8% of the irritant gas poisoning incidents. The top three industry categories reporting acute occupational poisoning incidents were manufacturing, wholesale and retail, and construction, which accounted for 70.6% of all incidents, while 67.5% of the deaths were reported in manufacturing, mining, and construction. The number of acute occupational poisoning incidents in small and micro-scale enterprises accounted for 38.3% and 31.4%, respectively. The fatality rate in small businesses (18.7%) was similar to that in large businesses (18.6%).  Conclusions  Acute occupational poisoning is a public health emergency with a high fatality rate in China. It is necessary to improve relevant laws and regulations, strengthen the surveillance and health emergency response capacity for acute occupational poisoning incidents, and take more targeted measures to prevent and control them.
Epidemiological characteristics of acute chemical poisoning cases in China from 2017 to 2021
ZHANG Yutao, JIANG Shaofeng, LANG Nan, HE Qian, ZHANG Hongshun
2023, 41(1): 43-48.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.010
[Abstract](8) [FullText HTML](0) [PDF 838KB](5)
  Objective  To analysis the epidemiological characteristics of acute chemical poisoning cases in China, and a provide evidence for establishment of prevention and control strategy against chemical poisoning.  Methods  A retrospective analysis of acute chemical poisoning cases in 87 hospitals from 26 provinces was carried out, including the time distribution, regional distribution, population distribution, varieties of toxicants, reason, exposure route and outcome, etc. The data were sorted out and analyzed by Excel and R 4.0.3.  Results  From 2017 to 2021, there were 11 724 cases of acute chemical poisoning, including 5 602 inpatient cases and 6 122 outpatient and emergency cases. Acute carbon monoxide poisoning accounted for 70.46% (8 261 cases), daily chemicals accounted for 7.89% (925 cases), and other chemicals accounted for 21.65% (2 538 cases). The number of poisoning cases was higher in men than in women. 72.69% poisoning cases were young and middle-aged people with labor ability. The number of poisoning cases decreased with the increase of education level (P < 0.01). Farmers (26.34%) ranked first, followed by workers (13.37%) and freelancers (8.53%). Acute carbon monoxide poisoning occurred frequently in winter and spring, and daily chemicals and other chemicals had no obvious seasonal trend. The top three cases were reported in Heilongjiang (24.58%), Sichuan (16.13%) and Guizhou (14.96%). Accidental poisoning cases accounted for 81.21% of the total cases. Occupational exposure was the second cause of poisoning, accounting for 8.38%. The distribution of poisoning causes of different poisons was statistically significant (P < 0.01). Accidental poisoning was more common in carbon monoxide poisoning cases, while occupational exposure and intentional poisoning were more common in other chemical poisoning cases. 83.34% of the patients with acute chemical poisoning had recovered or improved when they left the hospital, and the death cases accounted for 0.48%. The fatality rate of daily chemicals was the highest (1.19%), which increased with age.  Conclusions  The problem of acute chemical poisoning still exists and is more obvious in specific poisons, regions and populations. Therefore, it is necessary to establish a more sound poisoning monitoring system and formulate more scientific and accurate poison prevention and control strategies.
Discussion on sustainability pathways and strategies of the National Health Emergency Mobile Disposal Center for Acute Poisoning Accidents: an example of the"National(Shandong) Team"
WANG Dianguo, WANG Shanshan, MENG Chong, WANG Haiming
2023, 41(1): 49-51.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.011
[Abstract](7) [FullText HTML](0) [PDF 655KB](4)
Exploration and practice on construction, operation and capacity improvement of the national emergency response team for acute poisoning accidents: an example of the"National(Chongqing) Team"
WANG Shisong, TU Feng
2023, 41(1): 52-55.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.012
[Abstract](7) [FullText HTML](0) [PDF 774KB](4)
Thoughts on medical rescue of acute poisoning in chemical industry park
QIAO Li, ZHANG Jinsong
2023, 41(1): 56-59.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.013
[Abstract](10) [FullText HTML](0) [PDF 664KB](12)
There are the characteristics of high input, high output, high pollution, and high risk in the chemical industry. The construction of the chemical industry park has changed the previous loose and disorderly layout into a centralized and convenient for government management layout. To construct such a park, unified planning, unified design, a standardized production process, standardized risk assessment and risk prevention, and medical rescue should be achieved. However, because of the complex industrial characteristics of the chemical industry park, there is still a risk of leakage, explosion, and other accidents. Therefore, the appropriate emergency rescue system for chemical poisoning incidents should be developed in each park. As medical rescue bases and key institutions for treating the injured caused by poisoning accidents, comprehensive general hospitals must develop effective emergency plans and have the capacity for rapid emergency treatment in order to make the necessary preparations for poisoning health emergency medical rescue and cope with all types of emergencies, including events beyond the capacity for rapid deployment.
Correlation between actin-binding protein TRIOBP and susceptibility to noise-induced hearing loss
GAO Yunxia, ZHANG Jinwei, LI Yanru, QIU Congxi, RUAN Yanmei, ZHANG Yuxia, YE Cuiping, WANG Zhi
2023, 41(1): 60-66.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.014
[Abstract](4) [FullText HTML](0) [PDF 834KB](1)
  Objective  To analyze the relationship between polymorphisms of the actin-binding protein TRIOBP gene and noise-induced hearing loss (NIHL), so as to explore the genetic mechanisms underlying the occurrence of NIHL.  Methods  Noise-exposed workers who had undergone occupational health screening at several automobile manufacturing plants in Guangzhou from January to December 2020 were studied through a case-control study design, the noise-exposed workers with binaural high-frequency hearing thresholds above 25 dB (A) were selected as the high frequency hearing loss group, while those with hearing thresholds below 25 dB (A) in any binaural frequency band (500, 1 000, 2 000, 3 000, 4 000, 6 000 Hz) based on matching variables such as age, noise exposure level and job position were selected as the control group. There were 234 subjects in each group. The general information, occupational history, personal history, previous disease history, physical examination results and fasting whole blood samples of the subjects were collected. Blood samples from both groups of workers were sequenced for single nucleotide polymorphisms of the TRIOBP gene, and conditional logistic regression was used to show the genetic variation in TRIOBP in relation to susceptibility to NIHL.  Results  Univariate analysis showed that more workers in the high frequency hearing loss group had been exposed to mixed solvents and had prolonged sleep than those in the control group (P < 0.05); more workers in the control group than those in the high frequency hearing loss case group had auditory system symptoms, ALT abnormalities and LDL-C abnormalities (P < 0.05). Conditional logistic regression analysis showed that the five SNPs of TRIOBP gene were not the influencing factors of NIHL susceptibility (P> 0.05).  Conclusions  Mixed solvent exposure, sleep time, auditory system symptoms, abnormal ALT and LDL-C may be influential factors in noise-induced hearing loss. It cannot be considered that the genetic variation of TRIOBP is related to the susceptibility of NIHL.
Occupational stress status and its influencing factors of assembly -line workers in labor-intensive enterprises
LI Xiaoyi, CHEN Huiqing, YANG Min, GUO Yao, HUO Shaoxue, XU Ding
2023, 41(1): 67-72.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.015
[Abstract](5) [FullText HTML](0) [PDF 759KB](2)
  Objective  To explore the status and influencing factors of occupational stress among assembly-line workers in labor-intensive enterprises.  Methods  A total of 1 420 assembly-line workers from five labor-intensive enterprises in Foshan City were surveyed from August to September 2019 with the Effort-Reward Imbalance questionnaire. Binary logistic regression was used to analyze the influencing factors of occupational stress.  Results  Totally 1 228 valid questionnaires were collected, with a recovery rate of 86.48%. Occupational stress affected 42.02% of workers (516 out of 1 228). Regression analysis revealed that the risk of occupational stress of workers in the aluminum manufacturing group was 2.199 times greater than that of workers in the electronic manufacturing group(P < 0.01); the risk of occupational stress of shiftworkers was 1.745 times greater than that of day-shift workers (P < 0.01); and the risk of occupational stress of workers with working times of 2-4 and/or 5-9 years was 0.645 and 0.468 times greater than that of workers with working times less than 1 year (P < 0.05). The risk of occupational stress for workers with average monthly incomes higher than 5 000 yuan was 6.186 times that of workers with average monthly incomes less than 3 000 yuan (P < 0.01).  Conclusions  The level of occupational stress among assembly line workers in labor-intensive enterprises was high. It is suggested that enterprises reasonably arrange employees' duties, improve the performance system, appropriately improve their welfare benefits, and carry out mindfulness decompression therapy for those workers in the aluminum manufacturing industry engaged in shift work or with short working times and high average monthly income so as to alleviate their occupational tension.
High -frequency hearing loss of noise -exposure workers in bottled beverage manufacturing enterprises
PAN Wenna, LIU Keping, FENG Jianqing, CHEN Hao
2023, 41(1): 73-78.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.016
[Abstract](7) [FullText HTML](0) [PDF 817KB](1)
  Objective  To investigate the noise exposure level of workers in the production line of bottled beverage manufacturing enterprises in a city in the Pearl River Delta, and analyze the influencing factors of high-frequency hearing loss.  Methods  Totally 569 workers with at least 1 year of occupational noise exposure time in 7 bottled beverage manufacturing enterprises were studied; the noise exposure level, cumulative noise exposure (CNE), and high-frequency hearing loss (HFHL) of these workers were investigated. The effects of individual and/or occupational characteristics on the HFHL of noise-exposure workers were analyzed with a binary logistic regression model.  Results  The noise exposure level ranged from 72.3 to 96.7 dB (A), with 38.49% of the operation posts exceeding the national exposure limit. exposure limit. There were 109 workers with HFHL diagnosed, with prevalence of 19.16%. Obviously, the workers with HFHL(n = 109)were older and had a higher noise level, a higher CNE, and a longer noise exposure time compared with the other workers without HFHL (n = 460; P < 0.01). The most affected workers worked at posts with a high noise level, such as packaging, filling, batching and feeding, and bottle-blowing posts, while the noise level and cumulative noise exposure (CNE) of workers working at filling and bottle-blowing posts were highest (P < 0.05). The results of the logistic regression analysis showed that the risk of noise-exposure workers' HFHL increased by 1.034 and 1.444 times (P < 0.05) for an age increase of 1 year and a CNE increase of 1 dB (A) per year, respectively. Compared with workers working at posts without protective facilities, the risk of HFHL for workers working at posts with protective facilities decreased to 0.074 times (P < 0.05); compared with workers never wearing ear protectors, the risk of HFHL for workers occasionally and often wearing ear protectors was reduced to 0.357 and 0.254 times, respectively (P < 0.05).  Conclusions  The risk of a noise hazard at filling and bottle-blowing posts was high in the bottled beverage manufacturing industry. The measures, such as improving the automation of this production process, reducing workers' noise exposure time, and ensuring workers wear ear protectors, should be taken, and the hearing protection program for the workers working in the posts with high noise levels should be strengthened, in order to protect workers exposed to noise against the occurrence of HFHL.
Investigation on professional identity and perceived social support of nurses in standardized training under epidemic period in Shanghai
XU Huajiao, ZHANG Ying, WU Lingling, JIANG Lianqing, SHEN Weihong
2023, 41(1): 79-84.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.017
[Abstract](8) [FullText HTML](4) [PDF 866KB](0)
  Objective  To investigate the status of professional identity and perceived social support of nurses in standardized training nurses under specific epidemic period in Shanghai, and to understand the influencing factors on professional identity.  Methods  Convenience sampling was used to recruit 332 nurses for standardized training from three public general hospitals in Shanghai. General information and epidemic prevention-related behaviors, professional identity, and perceived social support were surveyed online using the Questionnaire Star Platform. Then, the survey data were analyzed by multiple linear regression analysis.  Results  Totally 320 valid questionnaires were collected, with a recovery rate of 96.4%. The total score of these nurses' professional identity was (108.44 ±19.94). The scores for each dimension, from high to low, were professional self-reflection, professional social support, professional frustration response, professional cognitive evaluation, and professional social skills. The total score of perceived social support was (61.74 ±12.54). The friend support score was the highest, while the family support score was the lowest. Multiple linear regression analysis showed that under the specific epidemic period in Shanghai, the nurses in standardized training with a bachelor's degree scored 9.058 points lower in professional identity than those with a junior college degree (P < 0.001). The score of nurses' professional identity increased by 3.339 points for each grade (unfamiliarity, familiarity, and mastery) increase in awareness of epidemic prevention and control knowledge (P = 0.003). The scores of professional identity of nurses in standardized training who participated in anti-epidemic volunteer service or had experience in fighting regional epidemics increased by 6.491 (P < 0.001) and 4.343 (P = 0.005), respectively, compared with those without such experience. For every 1 point increase in the perceived social support score, the professional identity score increased by an average of 1.064 points (P < 0.001).  Conclusions  The status quo of professional identity and perceived social support among nurses in standardized training were both at a medium level during the epidemic period in Shanghai in 2022. It is suggested that families, units, and all society should give more support and care to these nurses, and medical and health institutions should improve the nurse employment mechanism, take various measures to increase their knowledge of epidemic prevention and control, and encourage them to actively participate in volunteer service against epidemics so as to enhance their professional identity.
Survey on chromosome aberration rate of peripheral blood lymphocytes among radiological workers in Hunan Province
HU Xian, XING Yinghong, YUAN Huamin
2023, 41(1): 85-87.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.018
[Abstract](8) [FullText HTML](0) [PDF 547KB](2)
  Objective  To observe the chromosome aberration rate of peripheral blood lymphocytes of radiological workers in Hunan Province, so as to provide a basis for occupational protection and management against radiation hazards in Hunan Province.  Methods  A total of 1 243 radiological workers who underwent occupational health examinations in this hospital from 2020 to 2021 were studied. Among them, 514 staff engaged in interventional therapy, and 729 staff worked in the radiology department. The indicators of dicentromeric + centromeric ring (dic + r), acentric (ace)and abnormal chromosome aberration were observed.  Results  The rates of (dic + r) (0.03% ±0.23%), ace (0.01% ±0.13%) and abnormal chromosome aberration (2.335%)of staff engaged in intervention therapy were significantly higher than those in the radiology department (0.01% ±0.09%, 0.00% ±0.05%, 0.549%, respectively) (P < 0.05).Among the staff engaged in interventional therapy, no significant difference in rates of dic + r, ace, and chromosome aberration was found between the male staff and the female staff (P > 0.05); the rates of dic + r and chromosome aberration of the above 40-year-olds were higher than the below 40-year-olds (P < 0.05);and the rates of dic + r, ace, and chromosome aberration increased gradually with the service time (P < 0.05).  Conclusions  The chromosome aberration rate of staff engaged in interventional therapy was higher than that of staff in the radiology department. It is necessary to strengthen the occupational health management of these staff, improve personal protection awareness, and ensure their health and occupational safety.
Effects of different doses of Xuebijing injection on prognosis of patients with severe acute pancreatitis
NI Tongtian, CHEN Ying, ZHU Xiaojuan, CHE Zaiqian, MA Li, ZHAO Bing, ZHOU Weijun, MAO Enqiang, CHEN Erzhen
2023, 41(1): 88-92.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.019
[Abstract](5) [FullText HTML](0) [PDF 651KB](1)
  Objective  To investigate the efficacy of different doses of Xuebijing injection in the treatment of patients with severe acute pancreatitis, specifically the improvement of inflammatory indexes and organ function.  Methods  Patients with severe acute pancreatitis were divided into three groups: routine treatment (n = 70), low-dose Xuebijing treatment (n = 61), and high-dose Xuebijing treatment (n = 53). The patients were treated according to the guidelines for the treatment of acute pancreatitis, which included fluid resuscitation, etiology removal, and organ function maintenance; additionally, the patients in the Xuebijing treatment groups received Xuebijing (100 mL in low dose and 200 mL in high dose) in intravenous drip per day for ≥ 7 days. The inflammatory indexes, routine blood biochemical indexes, and organ function index scores, the proportion and timing of receiving invasive respiratory support treatment, and prognostic indexes including pancreatic necrosis score, laparotomy, hospitalization days, and mortality were compared among these groups.  Results  After one week of treatment, the white blood cells, scores of C-reactive protein and APACHE Ⅱ of patients in the high-dose group were significantly improved compared with those in the conventional treatment group (P < 0.05), while there was no significant difference between patients in the low-dose group and the conventional treatment group (P > 0.05). The time of mechanical ventilation [(9.59 ±7.43) d] in the high-dose Xuebijing treatment group was shorter than that in the low dose Xuebijing treatment group [(15.83 ±15.18) d] and the conventional treatment group [(20.96 ±23.29) d] (P < 0.05), while the difference was not statistically significant between the low dose treatment group and the conventional treatment group. Compared with the conventional treatment group, the proportion of laparotomy, hospitalization days in the high-dose group were significantly reduced (P < 0.05), but there was no significant difference in pancreatic necrosis score and mortality among these three groups (P > 0.05), and there was no significant difference in these four indicators between the low-dose Xuebijing treatment group and the conventional treatment group (P > 0.05).  Conclusions  Conventional therapy combined with high-dose Xuebijing therapy can effectively improve the inflammatory indexes and organ function of patients with severe acute pancreatitis, improve the prognosis, and shorten the hospitalization time.
Comparison of results of dust and noise hazard assessment in a stone processing enterprise using different risk assessment methods
LIU Mengmeng, ZHANG Jian, ZENG Qiang
2023, 41(1): 93-97.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.020
[Abstract](10) [FullText HTML](1) [PDF 591KB](2)
  Objective  Three methods for hazard assessment, the occupational hazard risk index method, the ICMM risk assessment model and the hazardous work classification method, were used to assess the dust and noise hazard assessment in a stone processing enterprise, and results were compared, in order to provide a basis for the establishment of occupational health risk assessment guidelines for stone processing in accordance with the actual situation.  Methods  A stone processing enterprise in Tianjin was studied, an occupational health survey and measurement of dust concentration and noise level at workplaces were done. Different risk assessment models were used to evaluate the health risks of dust and noise exposure, and the differences in results were compared.  Results  The raw material mainly used by the enterprise was natural marble. The engineering protection measures against dust were relatively perfect, while there were no engineering protection measures against noise, and workers' awareness of wearing protective equipment was poor. The results of the occupational hazard risk index method and hazardous work classification method showed that the marble dust hazard risk at all work positions was ranked as level 1, while the results of ICMM model showed that the risk at big plate cutting position was ranked level 1, and the risk at other positions was ranked as level 2. The results of the occupational hazard risk index method showed that the noise hazard risk at large plate cutting position was ranked as level 2, and the risk at other positions was ranked as level 3. The results of ICMM showed that the noise hazard risk at the large plate cutting position was ranked as level 4, and the risk at other positions was ranked as level 5. The results of the hazardous work classification method showed that the noise hazard risk at cutting, polishing and glue-repairing and grinding positions of large plates was ranked as level 1, and the risk at the other positions was ranked as level 2.  Conclusions  The three occupational health risk assessment methods can be used to assess the risk of dust and noise in stone processing enterprises. The ICMM model tends to overestimate the risk. The hazardous work classification method is relatively simple, while the occupational hazard risk index method can comprehensively consider various factors, and the evaluation results are relatively consistent with the actual situation.
Emergency management
PEST-SWOT analysis on application of unmanned aerial vehicle in health emergency response of chemical poisoning
TANG Shihao, LI Xin, ZHANG Jinwei, MAI qiuyuan, LIANG Jiabin, ZHOU Liping, WANG Zhi
2023, 41(1): 98-103.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.021
[Abstract](10) [FullText HTML](0) [PDF 922KB](0)
Personal protection of firefighters in public health emergencies
ZHANG Li'an, WANG Huifei
2023, 41(1): 104-107.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.022
[Abstract](7) [FullText HTML](0) [PDF 764KB](1)
Surveillance and practice
Method of fitting radiation dose-effect curves with Excel software
GAO Chaoxian, YANG Xueqing, LI Limei, ZHANG wen, FENG Wenting, YI Juan, HUI Changye
2023, 41(1): 108-112.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.023
[Abstract](5) [FullText HTML](0) [PDF 922KB](1)
  Objective  To explore the method of fitting radiation dose-effect curves with Excel software.  Methods  Based on the principles of the least-squares method and maximum-likelihood method, a data-input method was established in Excel, and a data processing formula was designed. Four commonly used radiation dose-effect curves were fitted using the least-squares method, and a quadratic polynomial curve was fitted using the maximum-likelihood method. The obtained results were compared with the curves fitted using the SPSS software and CABAS methods, or with the verified examples of dose-response curve fitting in authoritative references, to evaluate the difference between the curves fitted by the least- squares method and the maximum-likelihood method in the application of dose estimation.  Results  Four commonly used radiation dose-effect curves were successfully established with Excel software by the least-squares method, and their parameters were consistent with the curves fitted by using SPSS software; the quadratic polynomial curve established with Excel software by the maximum-likelihood method was consistent with the curve fitted by CABAS software; the parameters of curve fitting were the same as those of the examples in the reference.  Conclusions  Excel software can be used to fit and establish a radiation biological dose effect curve, which is convenient for biological dose estimation in the laboratory, especially for the estimation of large batches of samples.
Similarities and differences between hazard classification and transportation classification based on analysis of hazardous chemicals types
PU Zhengyu, HUANG Chaozheng, CHEN Yushuang
2023, 41(1): 113-116.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.024
[Abstract](6) [FullText HTML](0) [PDF 476KB](1)
Research progress on occupational hazards and biomarkers of low-concentration benzene
ZHANG Naixing, WANG Dianpeng, FENG Guangquan, LIN Dafeng, GUO Yan, DENG Lidan, YANG Xiangli, LI Peimao, ZHANG Zhimin, ZHANG Wen, FENG Weiting
2023, 41(1): 117-121.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.025
[Abstract](9) [FullText HTML](5) [PDF 761KB](2)
Progress in the mechanism of pulmonary fibrosis induced by carbon nanotubes
ZHANG Jiazhen, YANG Yang, ZHANG Xiaoli, LI Bo, ZHANG Jing
2023, 41(1): 122-126.   doi: 10.16369/j.oher.issn.1007-1326.2023.01.026
[Abstract](6) [FullText HTML](0) [PDF 1370KB](0)
Intervention of mental health risks of female nurses engaged in nursing patients with
YU Wenlan, SUN Daoyuan
2020, 38(2): 106-108, 151.   doi: 10.16369/j.oher.issn.1007-1326.2020.02.002
[Abstract](653) [FullText HTML](254) [PDF 693KB](37)
Characteristics of occupational disease reported in China during 2009 to 2018
WANG Haitao, YANG Li, SU Yajiao, QIN Zhenwei, ZHANG Xiaotong, LI Chan, ZHU Hongru, FAN Hongmin
2020, 38(2): 178-182.   doi: 10.16369/j.oher.issn.1007-1326.2020.02.022
[Abstract](846) [FullText HTML](286) [PDF 901KB](98)
Health effects of cobalt and its compounds
LIU Wuzhong, WANG Jianmin, ZHANG Hong, HUANG Hutao
2016, 34(2): 111-113.   doi: 10.16369/j.oher.issn.1007-1326.2016.02.007
[Abstract](787) [PDF 424KB](31)
Development history and prospect of pneumoconiosis prevention and treatment in China
LI Zhimin
2019, 37(5): 397-401.   doi: 10.16369/j.oher.issn.1007-1326.2019.05.001
[Abstract](611) [FullText HTML](210) [PDF 2920KB](48)
Investigation on the current situation of occupational health technical service institutions in Shanghai and analysis on the quality of technical services
2016, 34(3): 203-206.   doi: 10.16369/j.oher.issn.1007-1326.2016.03.008
[Abstract](428) [PDF 461KB](16)
Characteristics of chronic occupational n-hexane poisoning cases in Shenzhen from 2006 to 2015
GUO Meiqiong, GUO Xiang, LIN Hui, HE Jian
2016, 34(2): 107-110.   doi: 10.16369/j.oher.issn.1007-1326.2016.02.006
[Abstract](385) [PDF 512KB](2)
Present situation and problem of pneumoconiosis prevention and control in coal mines and proposed countermeasures in China
FAN Jingguang, ZHANG Jianfang, WANG Haijiao, WANG Xuetao, TANG Aihua, LIU Qicai
2021, 39(1): 1-5.   doi: 10.16369/j.oher.issn.1007-1326.2021.01.001
[Abstract](440) [FullText HTML](276) [PDF 798KB](76)
Comparison of domestic and foreign standards for medical personal protective equipment
LANG Nan, YUAN Yuan, ZHOU Jing
2020, 38(2): 112-115.   doi: 10.16369/j.oher.issn.1007-1326.2020.02.004
[Abstract](465) [FullText HTML](162) [PDF 575KB](24)
Investigation on mass event of occupational n-hexane poisoning and suggestion of countermeasures
HU Liecong, YE Lihe, FAN Yanqiong, ZHUNG xiaozhou
2017, 35(4): 393-395.   doi: 10.16369/j.oher.issn.1007-1326.2017.04.030
[Abstract](262) [FullText HTML](83) [PDF 8046KB](5)
Study of clinical characteristics of mercury poisonings via different exposure routes
ZHANG Yili, LIU Weiwei, LIU Yimin
2015, 33(4): 234-237.   doi: 10.16369/j.oher.issn.1007-1326.2015.04.002
[Abstract](391) [PDF 601KB](2)