Abstract: Objective To evaluate the effect of two arrangements of long-distance transfer of critically ill patients. Methods Totally 516 critically ill patients in Yingcheng were transferred to Wuhan,of whom 214 cases were previously accompanied by general clinical doctors and nurses (first group),while 302 cases by pre-hospital emergency doctors and nurses (second group).The association of patients'fate with these accompanying modes was evaluated. Results The transferring time was (121 ±8) min for first group patients,while (90 ±8) min for second group patients.Among the first group,63 cases had unstable vital signs,18 cases had suffocation and 6 cases died,while in the second group,45 cases had unstable vital signs,12 cases had suffocation and 5 cases died,respectively.It showed that the first group patients had longer transferring time (t=1.028,P<0.05),increased rates of stable vital signs and suffocation (χ²=15.997,4.504,respectively,P<0.05). Conclusion The accompany by pre-hospital emergency doctors and nurses is good for the long-distance transfer of critically ill patients.