吸烟与急性心肌梗死患者血脂及冠状动脉病变程度的相关性研究

徐元杰; 陈缙; 陈小燕; 孔繁亮; 吴同果

doi:10.16369/j.oher.issn.1007-1326.2016.02.004

吸烟与急性心肌梗死患者血脂及冠状动脉病变程度的相关性研究

暨南大学医学院附属广州红十字会医院心血管内科, 广东广州 510220

详细信息

作者简介:
徐元杰(1976-),男,硕士,主治医师

中图分类号: R163.2
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出版历程
- 收稿日期: 2015-11-06

Correlation between smoking and blood lipid and coronary artery lesions in patients with acute myocardial infarction

Department of Cardiovascular Diseases, Red Cross Hospital of Guangzhou Affiliated to Medical College of Jinan University, Guangzhou, Guangdong 510220, China

摘要

摘要: 目的观察吸烟与急性心肌梗死患者血脂水平和冠状动脉病变程度的相关性。方法选取129例急性心肌梗死患者为研究对象,参照国际公认的吸烟指数分级法将上述患者分为0级(43例)、1级(33例)、2级(31例)、3级(22例)四类患者,比较不同吸烟指数患者甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)水平变化,同时以Judkins法经股动脉进行选择性冠状动脉造影,观察不同吸烟指数患者冠状动脉病变支数情况。结果 0~3级吸烟患者TC、TG、LDL-C水平呈上升趋势(r=0.747、0.914、0.833,P<0.05),其中吸烟3级指数患者TG高于0、1级,而LDL-C高于0级,差异有统计学意义(P<0.05);吸烟指数1、2、3级指数患者三支病变发生率高于0级,差异有统计学意义(P<0.05/6);三支病变发生率随吸烟指数级别上升呈上升趋势(r=0.863,P<0.05)。结论吸烟可影响急性心肌梗死患者血脂水平,且吸烟指数越高,病变程度越严重,需引起临床重视。
- 吸烟 /
- 急性心肌梗死 /
- 血脂 /
- 冠脉病变程度
+ English
Abstract: Objective To observe the correlation between smoking and blood lipid level and degree of coronary artery lesions in patients with acute myocardial infarction. Methods Totally 129 patients with acute myocardial infarction were studied. According to the internationally recognized smoking index classification method, the above patients were divided into 4 groups as grade 0 (43 cases), grade 1 (33 cases), grade 2 (31 cases) and grade 3 (22 cases). The changes of triglyceride (TG), total cholesterol (TC), high density lipoprotein cholesterol (HDL-C) and low density lipoprotein cholesterol (LDL-C) of patients with different smoking indexes were compared. At the same time, Judkins method was used to implement elective coronary angiography via femoral artery. The number of coronary artery lesions in patients with different smoking indexes was observed. Results TC, TG and LDL-C of patients in the grade 0-3 groups showed an increasing trend (r=0.747, 0.914,0.833, respectively, P<0.05) and TG of patients in grade 3 group was significantly higher than that of patients in the grade 0 and 1 groups, while LDL-C was significantly higher than that of patients in grade 0 group (P<0.05).The prevalence of three-vessel lesion of patients in grade 1, 2 and 3 groups was significantly higher than that of patients in grade 0 groups,respectively(P<0.05/6). The prevalence of three-vessel lesion showed an increasing trend with increasing smoking indexes(r=0.863, P<0.05). Conclusion Smoking can affect the blood lipid level in patients with acute myocardial infarction,which needs more clinical attention.
- smoking /
- acute myocardial infarction /
- blood lipid /
- degree of coronary artery lesion

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参考文献(9)

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施引文献(7)

期刊类型引用(2)

1.	韩凤杰. 心血管疾病与血脂关系的研究进展. 继续医学教育. 2017(06): 135-137 . 百度学术
2.	包博. 不同年龄急性心肌梗死患者血脂异常及冠状动脉病变的对比分析. 中国医药指南. 2017(15): 135-136 . 百度学术

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文章访问数: 201
HTML全文浏览量: 18
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被引次数: 7

吸烟与急性心肌梗死患者血脂及冠状动脉病变程度的相关性研究

作者简介: 徐元杰(1976-),男,硕士,主治医师

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出版历程

Correlation between smoking and blood lipid and coronary artery lesions in patients with acute myocardial infarction

期刊类型引用(2)

其他类型引用(5)

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作者简介:
徐元杰(1976-),男,硕士,主治医师