Abstract: Objective To explore the effect of different rehabilitation treatment and nursing methods in the improvement of pulmonary function and arterial blood gas condition of pneumoconiosis patients at stable stage. Method Totally 120 pneumoconiosis patients at stable stage during January 2012 to August 2015 were treated in different ways, namely the regular group(A), the exercise training group(B),the noninvasive ventilation group(C) and the integrated exercise training and noninvasive ventilation group(D). After 3 months of rehabilitation treatment,the varied therapeutic indexes were measured and compared among different groups. Results There were no differences of various observed indexes among the patients in different groups before they received the treatment. It was noted that the MVV and DLCO in all patients had been improved after 3 months' treatment. With further comparison,MVV of group B,C and D was better than that of group A;MVV of group C and D was better than that of group B; DLCO of group D was better than that of group A and B, and the differences were statistically significant (P<0.05). After intervention, the lung function(FVC and DLCO) of patients in group D were significantly improved(P<0.05). MVV of patients of group B, C and D were significantly improved compared with that before intervention, and the difference was statistically significant (P<0.05). PaO₂,SpO₂ of group C and D were better than those of group A and B(P<0.05).Through comparison of arterial blood gas of the patients in each group,PaO₂ and SpO₂ of group C and D were significantly improved after intervention,and the difference was statistically significant (P<0.05). Conclusion The rehabilitation nursing with integrated exercise training and noninvasive ventilation is more effective in the treatment of pneumoconiosis patients at stable stage.