摘要:
目的 研究尘肺病患者胸部螺旋CT与肺功能变化的关系,探讨尘肺病患者肺损伤的评估方式。 方法 检查91例尘肺病患者胸部螺旋CT和肺功能,对胸部CT不同影像改变与肺功能变化结果进行比较分析。 结果 胸部螺旋CT表现为双肺肺野不同区域弥漫性分布的圆形小阴影、小阴影聚集和大阴影;75.82%的患者表现为不同程度的肺功能损伤,主要为限制性和混合性通气障碍以及弥散障碍;随着阴影分布扩大和聚集,肺功能损伤的异常率逐渐升高(P<0.05);大阴影组FEV1、MVV、DLCO与其他各组比较,VC、FVC、FEV1/FVC、RV/TLC与上肺野、上中肺野小阴影分布组比较,以及小阴影聚集组DLCO与上肺野、上中肺野小阴影分布组比较,差异均有统计学意义(P<0.05)。各组肺功能损伤类型和肺通气功能损伤类型差异无统计学意义(P>0.05)。 结论 胸部螺旋CT能在一定程度上反映尘肺病患者肺功能变化,但它和肺功能是评价尘肺病肺损伤的两种独立方法,不能相互替代,两者联合检查有助于尘肺病的病情观察和诊断鉴定。
关键词:
-
尘肺
/
-
胸部螺旋CT
/
-
肺功能
/
-
小阴影
/
-
大阴影
+ English
Abstract:
Objective To study the relationship between the lung function and chest image derived by spiral CT examination of pneumoconiosis patients,and to seek the best method to assess chronic lung injure degree. Methods The paired data of lung function parameters and chest spiral CT image of 91 pneumoconiosis cases were carefully analyzed. Results The main changes of chest spiral CT image were small opacity, aggregation of small opacity and large opacity diffusely scattered in the whole lung. The lung function examination showed that 75.82% patients had abnormality of lung function. The damages of lung function were mainly the restrictive and mixed ventilation dysfunction or diffusion dysfunction. The lung function parameters, such as VC,FVC,RV/TLC, FEV1, FEV1/FVC, MVV and DLCO of patients with large opacity were different with those of the other patients(P<0.05). DLCO of patients with aggregation of small opacity was different with that of patients with nodule in upper lobe or upper and middle lobe of the lungs (P<0.05). There was no internal relation between the lung function parameters and chest image characteristics, though it seemed there was higher abnormality of lung function among patients with more or bigger nodules. Conclusion The lung function examination and chest spiral CT image examination are independent methods in assessing lung injure degree of pneumoconiosis. The two methods altogether could contribute to observe the patients with pneumoconiosis and make the diagnosis accurately.
百度学术
下载:
