唐美岸, 许金桂, 余燕湘, 彭胜, 陈奇, 朱香, 肖雄斌. 融合灶总体积对叁期尘肺病患者肺功能评估的意义[J]. 职业卫生与应急救援, 2017, 35(4): 305-307. DOI: 10.16369/j.oher.issn.1007-1326.2017.04.002
引用本文: 唐美岸, 许金桂, 余燕湘, 彭胜, 陈奇, 朱香, 肖雄斌. 融合灶总体积对叁期尘肺病患者肺功能评估的意义[J]. 职业卫生与应急救援, 2017, 35(4): 305-307. DOI: 10.16369/j.oher.issn.1007-1326.2017.04.002
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TANG Mei'an, XU Jingui, YU Yanxiang, PENG Sheng, CHEN Qi, ZHU Xiang, XIAO Xiongbin. Total volume of progressive massive fibrosis and pulmonary function of pneumoconiosis patients at stage Ⅲ[J]. Occupational Health and Emergency Rescue, 2017, 35(4): 305-307. DOI: 10.16369/j.oher.issn.1007-1326.2017.04.002
Citation: TANG Mei'an, XU Jingui, YU Yanxiang, PENG Sheng, CHEN Qi, ZHU Xiang, XIAO Xiongbin. Total volume of progressive massive fibrosis and pulmonary function of pneumoconiosis patients at stage Ⅲ[J]. Occupational Health and Emergency Rescue, 2017, 35(4): 305-307. DOI: 10.16369/j.oher.issn.1007-1326.2017.04.002
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融合灶总体积对叁期尘肺病患者肺功能评估的意义

Total volume of progressive massive fibrosis and pulmonary function of pneumoconiosis patients at stage Ⅲ

    摘要
  • 摘要:
    目的 分析融合灶(progressive massive fibrosis, PMF)总体积(VPMF)与肺功能的相关性, 探讨VPMF对叁期尘肺患者肺功能评价的意义, 为临床评估叁期尘肺病患者的肺功能提供参考。
    方法 收集2016年1-9月收治的叁期尘肺病并发PMF患者52例, 测量患者VPMF, 收集其肺功能指标, 并对结果进行相关分析和回归分析。
    结果 52例叁期尘肺病合并PMF患者肺功能主要损害特点是混合性肺通气功能障碍。患者VPMF范围为5.63~258.8 cm3; 与其第一秒用力呼气量占预计值比值(FEV1/Pre)、用力肺活量占预计值比值(FVC/Pre)、肺一氧化碳弥散量占预计值比值(DLCO/Pre)均呈负相关(rs=-0.74、-0.65、-0.72, P < 0.05);以VPMF为自变量, FEV1/Pre、FVC/Pre、DLCO/Pre分别为应变量, 进行线性回归分析所得方程分别为:FEV1/Pre=0.87-0.003×VPMF (R2=0.58、F=68.6, P < 0.01);FVC/Pre=0.91-0.002×VPMF (R2=0.45、F=41.6, P < 0.01);DLCO/Pre=0.94-0.002×VPMF (R2=0.53、F=56.8, P < 0.01)。
    结论 可通过测量融合灶总体积大致预计FEV1/Pre、FVC/Pre及DLCO/Pre值。

     

    Abstract:
    Objective The volume of progressive massive fibrosis(VPMF) and lung function of pneumoconiosis patients at stage Ⅲ were observed and their correlation was evaluated.
    Methods A total of 52 pneumoconiosis patients at stage Ⅲ complicated with PMF were observed during January to September, 2016. The patients' lung function was measured and the VPMF was calculated based on the results of CT examination. Then the correlation between these two indicators was analyzed.
    Results The main features of lung dysfunction of these 52 patients was mixed pulmonary ventilation dysfunction. The VPMF of the patients varied from 5.63 to 258.8 cm3, and it was negatively correlated with FEV1/Pre, FVC/Pre, and CO diffusion/Pre (rs=-0.74, -0.65, -0.72, P < 0.05, respectively). The corresponding linear regression equations were FEV1/Pre=0.87-0.003×VPMF(R2=0.58, F=68.6, P < 0.01), FVC/Pre=0.91-0.002×VPMF (R2=0.45, F=41.6, P < 0.01), and CO dispersion/Pre=0.94-0.002×VPMF (R2=0.53, F=56.8, P < 0.01), respectively.
    Conclusion We can estimate FEV1/Pre, FVC/Pre and CO diffusion/Pre based on the total volume of progressive massive fibrosis.

     

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