Abstract: At present，the prevention on coronavirus disease 2019 （COVID -19） is at a critical stage，we should help enterprises to resume production in a safe and orderly manner under the premise of effective prevention and control of the epidemic. During this specific period，the enterprise should make overall arrangements on the work of occupational health examination. This article analyzed the possible infection risk on occupational health surveillance under the outbreak of COVID-2019，and formulated the corresponding prevention and control countermeasures in the process of occupational health surveillance. The medical institutions should arrange physical examination reasonably and normatively in the four stages of occupational health surveillance： preparation，pre-examination，examination and post-examination. Such measures can ensure both well-done of occupational health work and prevention of infection during outbreak of COVID-2019.