付丽丽, 那向杰, 段潇潇, 王丽东. 2020—2021年沈阳市386名放射诊疗医务人员健康状况调查[J]. 职业卫生与应急救援, 2023, 41(3): 291-295. DOI: 10.16369/j.oher.issn.1007-1326.2023.03.007
引用本文: 付丽丽, 那向杰, 段潇潇, 王丽东. 2020—2021年沈阳市386名放射诊疗医务人员健康状况调查[J]. 职业卫生与应急救援, 2023, 41(3): 291-295. DOI: 10.16369/j.oher.issn.1007-1326.2023.03.007
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FU Lili, NA Xiangjie, DUAN Xiaoxiao, WANG Lidong. Investigation on the health status of 386 radiation workers in Shenyang from 2020 to 2021[J]. Occupational Health and Emergency Rescue, 2023, 41(3): 291-295. DOI: 10.16369/j.oher.issn.1007-1326.2023.03.007
Citation: FU Lili, NA Xiangjie, DUAN Xiaoxiao, WANG Lidong. Investigation on the health status of 386 radiation workers in Shenyang from 2020 to 2021[J]. Occupational Health and Emergency Rescue, 2023, 41(3): 291-295. DOI: 10.16369/j.oher.issn.1007-1326.2023.03.007
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2020—2021年沈阳市386名放射诊疗医务人员健康状况调查

Investigation on the health status of 386 radiation workers in Shenyang from 2020 to 2021

    摘要
  • 摘要:
      目的  探讨低剂量电离辐射对放射诊疗医务人员健康的影响。
      方法  选取2020—2021年在辽宁省疾病预防控制中心进行职业健康检查的放射诊疗医务人员386人为接触组，以近期参加了放射岗位上岗前和待转岗健康检查的174名人员为对照组，检测两组人群血细胞计数、外周血淋巴细胞染色体畸变及微核细胞率（简称“微核率”），对数据进行统计分析。
      结果  接触组淋巴细胞（LY）计数低于对照组，染色体畸变率及检出率、微核率及检出率均高于对照组（P < 0.01）。多元线性回归分析结果显示：分别相比隔室操作组的放射诊疗医务人员和男性放射诊疗医务人员，近台同室操作的介入组放射诊疗医务人员和女性放射诊疗医务人员的LY计数均降低（β=-0.182、-0.159，P < 0.05）；随着工龄增加，放射诊疗医务人员LY计数也降低（β=-0.008，P < 0.05）。泊松回归分析结果显示：相比隔室操作组的放射诊疗医务人员，介入组放射诊疗医务人员的染色体畸变率及微核率均升高（RR = 4.078、1.359，P < 0.05）；随着工龄增加，放射诊疗医务人员的染色体畸变率及微核率也均升高（RR = 1.050、1.024，P < 0.05）。
      结论  长期低剂量电离辐射对放射诊疗医务人员LY计数、外周血淋巴细胞染色体畸变及微核有不同程度的影响，应进一步加强针对介入放射诊疗医务人员的职业健康监护，减少辐射损伤。

     

    Abstract:
      Objective  To investigate the effects of low-dose ionizing radiation on the health of radiological medical staff.
      Methods  A total of 386 radiological medical staff who underwent occupational health examinations at the Liaoning Provincial Center for Disease Control and Prevention from 2020 to 2021 were studied, and 174 staff who recently participated in the preand post-transfer health examinations for radiological posts were selected as the reference group. The blood cell counts, peripheral blood lymphocyte chromosome aberrations, and micronucleus rates of the two groups were analyzed.
      Results  The lymphocyte count of the radiation workers was lower than that of the reference group, and the chromosome aberration rate and abnormality rate, micronucleus rate, and abnormality rate were higher than those of the reference group (P < 0.01). The results of multiple linear regression analysis showed that compared with the radiological medical staff who operated in separate rooms or male radiological medical staff, the lymphocyte count of the interventional therapists who operated in the same room near the table and female radiological medical staff was reduced (β=-0.182, -0.159, P < 0.05); with the increase in working time, the lymphocyte count of radiological medical staff also decreased (β=-0.008, P < 0.05). The results of Poisson regression analysis showed that compared with the radiological medical staff who operated in separate rooms, the chromosome aberration rate and micronucleus rate of the interventional therapists increased (RR = 4.078, 1.359, P < 0.05); with the increase of working years, the chromosome aberration rate and micronucleus rate of the radiological medical staff also increased (RR = 1.050, 1.024, P < 0.05).
      Conclusions  Long-term low-dose ionizing radiation had varying degrees of impact on lymphocyte count, peripheral blood lymphocyte chromosome aberration, and the micronucleus of radiological medical staff. Further occupational health monitoring should be strengthened for radiological medical staff engaged in interventional therapy to reduce radiation damage.

     

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