摘要:
[目的]了解广东省佛山市三水区正常人群体全血中13种重金属含量,并与其他地区的文献资料作比对,为防控重金属污染及其健康危害提供依据。[方法]采用多阶段分层整群随机抽样法,抽取正常人群共862份全血样本,采用离子耦合质谱法(ICP-MS)检测铅、汞、镉等13种重金属含量。[结果]正常人群中全血重金属含量5%位数、中位数、95%位数分别为:血钒0.62、0.99、1.57 μg/L;血铜504.3、661.2、844.4 μg/L;血锌3 056、4 917、7 126 μg/L;血锗193.4、274.6、389.5 μg/L;血砷1.55、4.23、7.29 μg/L;血硒232.4、306.0、392.6 μg/L;血铷2 595、3 403、4 399 μg/L;血锶8.42、13.83、23.63 μg/L;血镉0.34、0.98、2.09 μg/L;血锑4.18、5.38、6.71 μg/L;血铯3.81、6.39、10.17 μg/L;血汞0.25、1.86、4.68 μg/L;血铅15.72、31.13、51.40 μg/L,且大部分存在性别和年龄间的统计学差异。[结论]三水地区正常人群全血主要重金属含量水平较高,原因可能与实验室间差异、饮食习惯和环境重金属污染有关;部分重金属含量之间存在相关关系,提示该地区应加强重金属污染的防控并进一步探讨重金属间的相互关系。
+ English
Abstract:
[Objective] To understand blood concentrations of 13 heavy metals among general population in Sanshui district of Foshan, compare with the reference values reported by the literature and provide the background information on strategy making for prevention and control of heavy metal pollution in this area. [Methods] A total of 862 cases were selected by using multistage stratified random sampling method. Their blood samples were collected and blood levels of 13 heavy metals were analyzed with ICP-MS. The results were compared with the reported reference values and suggestion on control heavy metal pollution was given based on the known situation of local industries. [Results] Blood levels of 13 heavy metals among these population (5%, median and 95% percentile,μg/L) were as below:vanadium 0.62, 0.99 and 1.57; copper 504.3, 661.2 and 844.4;zinc 3 056, 4 917 and 7 126; germanium 193.4, 274.6 and 389.5; arsenic 1.55,4.23 and 7.29;selenium 232.4,306.0 and 392.6; rubidium 2 595,3 403 and 4 399; strontium 8.42,13.83 and 23.63; cadmium 0.34,0.98 and 2.09; antimony 4.18,5.38 and 6.71; cesium 3.81,6.39 and 10.17; mercury 0.25,1.86 and 4.68; lead 15.72,31.13 and 51.40. The blood concentrations of these heavy metals varied among different ages and genders and seemed a little bit higher than the reported reference values in other areas. [Conclusion] The general population had a higher blood level of some heavy metals in Sanshui district. Except for the variation of laboratory analysis, the dietary habits of local persons and environmental heavy metal pollution maybe make contribution. It indicate that it is important to protect environment in this area.
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