Abstract: 1-Bromopropane is widely used as an alternative to ozone layer-depleting solvents such as chlorofluorocarbons. However,human cases intoxicated with 1-bromopropane and epidemiological studies showed that 1-bmmopropane has potential neurotoxic effects on human beings with symptoms and signs including diminished peripheral nervous conduction velocity and vibration sense in the lower extremities as well as ataxic gait. This paper reviews briefly the updated studies on neurotoxicity of 1-bromopropane.